Brewery waste poses a management challenge for microbreweries, yet it contains nutrients and organic carbon that can benefit soil health and fertility. Microbreweries located in resource-limited communities such as Appalachian region of southeast Ohio can help aspiring organic farmers overcome financial and technical barriers to become USDA certified organic. This planning project explored the technological, regulatory, and socio-economic opportunities and challenges of processing brewery waste by anaerobic digestion (AD) to yield biogas energy and digestate residue suitable for use as an organic soil amendment.